Major histocompatibility complex (MHC)

Located on human chromosome 6, the MHC is a highly polymorphic set of genes that encode for molecules essential to self/non-self discrimination and antigen ...

2024年4月9日 — Major histocompatibility complex (MHC), group of genes that code for proteins found on the surfaces of cells that help the immune system ...

由 DC Dearborn 著作 · 2022 · 被引用 6 次 — Across jawed vertebrates, the genes of the major histocompatibility complex (MHC) make cell‐surface proteins that display pathogen peptides to the immune system ...

The major histocompatibility complex (MHC) is comprised of cell membrane proteins that deliver short peptides to the cell surface, presenting these peptide ...

由 AJ Tomlinson 著作 · 1997 · 被引用 2 次 — Sequencing MHC class I peptides using membrane preconcentration-capillary electrophoresis tandem mass spectrometry (mPC-CE-MS/MS) · Publisher Summary · References.

由 AJ Tomlinson 著作 · 1996 · 被引用 50 次 — The presentation of MHC class I peptides at cell surfaces and the subsequent cytolytic T-lymphocyte response are critical components of the mammalian immune ...

2013年10月31日 — 人類的MHC 蛋白可以分為兩大類：第一型MHC 分子（class I MHC）和第二型MHC 分子（class II MHC），前者位於個體中所有有核的細胞上，後者則只分布在抗原 ...

MHC與人類的免疫系統功能密切相關，其中部分基因編碼細胞表面抗原，成為每個人的細胞不可混淆的「特徵」，是免疫系統區分本身和異體物質的基礎。